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KMID : 0372919840050020143
Journal of Biomedical Engineering Research
1984 Volume.5 No. 2 p.143 ~ p.148
The Study on Electromagnetic Stimulator for Healing of Ununited Fracture
Lee GK
Han
Abstract
AB-type block copolymers of poly(r-benzyl L-glutamate) (PBLG, a segment) and polyoxypropylene (POP, Bsegment) were synthesized and they were reacted with polyoxypropylene bis(6-aminohexyl) (POE) to enhance the hydrophilicity of the polymers. The degree of swelling of the POE-crosslinked block copolymers (CPB -2) was higher than that of the block dopolymers (PB). The amount of 5-fluorouracil re-leased from CPB-2 block copolymers was greater than that from the PB block copolymers when they were incubated In the same period. These results indicate that the amount of 5-fluerouracil released from the matrices is proportional to the hydrophilicity of the polymers. Observing polymer surfaces by scanning electron microscope, pores (diameter, 0.5-1.5¥ìm) were appeared on the surface of CPB-2
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